graphic of PTSD brain concept

Finding Relief and Hope: The Transformative Benefits of Ketamine Infusion Therapy for PTSD

Next month (June) is PTSD Awareness Month. As a clinic specializing in depressive mood disorders, PTSD being one of them, we thought it was essential to look at how Ketamine Infusion Therapy can help. Post-Traumatic Stress Disorder (PTSD) can profoundly impact an individual’s mental health, relationships, and overall quality of life. Fortunately, advancements in medical science have led to innovative treatments that offer renewed hope for individuals struggling with PTSD. One such groundbreaking therapy is Ketamine Infusion Therapy, which has shown remarkable benefits in alleviating the symptoms of PTSD. 

Understanding PTSD:

Post-Traumatic Stress Disorder is a mental health condition that can develop after experiencing or witnessing a traumatic event. The symptoms may include vivid flashbacks, nightmares, severe anxiety, insomnia, and emotional distress. Conventional treatments, such as therapy and medication, have proven effective for many, but some individuals continue to experience distressing symptoms despite these interventions. This is where Ketamine Infusion Therapy comes into play.

The Promise of Ketamine Infusion Therapy:

Ketamine, a dissociative anesthetic initially developed for use in surgery, has gained recognition in recent years for its potential to treat various mental health conditions, including PTSD. 

Scientific Evidence:

Recent studies have supported the efficacy of Ketamine Infusion Therapy in reducing the symptoms of PTSD. For example, published on January 5, 2021, in the American Journal of Psychiatry, it was the first randomized, controlled trial of repeated ketamine administration for chronic PTSD. It suggests ketamine may be a promising treatment for PTSD patients. 

“Our findings provide insight into the treatment efficacy of repeated ketamine administration for PTSD, an important next step in our quest to develop novel pharmacologic interventions for this chronic and disabling disorder, as a large number of individuals are not sufficiently helped by currently available treatments,” says Adriana Feder, MD, Associate Professor of Psychiatry at the Icahn School of Medicine at Mount Sinai and lead author of the study. “The data suggests repeated IV ketamine is a promising treatment for people who suffer from PTSD and provides evidentiary support to warrant future studies to determine how we can maintain this rapid and robust response over time.”

Imaging analysis was conducted on the participants in a follow-up to the above study. The team analyzed detailed brain imaging data of individuals with chronic PTSD treated in the clinical trial with ketamine. Results suggest that improvements in PTSD symptoms observed in the trial were related to specific ketamine-induced changes in connectivity between several brain regions.

How Ketamine Works:

Ketamine works differently from traditional antidepressants by targeting the brain’s glutamate system, a neurotransmitter involved in mood regulation. It enhances the growth of new connections between brain cells, leading to improved neural pathways and enhanced emotional resilience. This unique mechanism of action allows for rapid relief from symptoms, often within hours or days, compared to the weeks or months required for traditional treatments to take effect.

Minimal Side Effects:

Ketamine Infusion Therapy is generally well-tolerated, with minimal side effects reported. Patients may experience mild dissociation during the infusion, which is typically temporary and subsides shortly after the treatment. 

Long-Term Relief and Enhanced Well-being:

One of the most promising aspects of Ketamine Infusion Therapy is its potential to provide lasting relief. While the number of treatments required may vary from person to person, many patients report a significant reduction in PTSD symptoms that begin immediately after treatment and can last weeks. With ongoing treatment, relief enables individuals to regain control of their lives, rebuild relationships, and experience an improved overall sense of well-being.

For individuals grappling with the distressing symptoms of PTSD, Ketamine Infusion Therapy can offer a beacon of hope. Backed by scientific research, this innovative therapy can bring transformative relief, allowing individuals to reclaim their lives from the grip of PTSD. If you are seeking a path toward healing and renewed well-being, consider exploring the possibilities of Ketamine Infusion Therapy as a powerful tool in your journey toward recovery.

For more information on treatment and costs, contact Tranquility Ketamine at (505) 639-4973 or visit