chronic pain relief

When Pain Becomes the Background Noise of Your Life

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If you live with chronic pain, you know it’s rarely just about the pain itself. It’s the alarm you set to take medication before you’re even fully awake. It’s the plans you quietly cancel because you can’t be sure how your body will feel that day. It’s the fatigue that builds not just from the pain, but from the constant bracing for it. Slowly, pain starts to work its way into your days, your relationships, and your sense of what’s still possible for you.

At Tranquility Ketamine, we talk with people every week who have tried nearly everything: physical therapy, medications, injections, specialists upon specialists. Many are exhausted, not just by their pain, but by the search for something that actually helps. That’s why we want to talk about a different way of understanding chronic pain, and why ketamine infusion therapy has become such a meaningful option for so many of our patients.

Your Nervous System Can Get “Stuck”

Pain is supposed to be a messenger. It signals to your brain that something is wrong, so you can protect yourself. But with chronic pain conditions like fibromyalgia, neuropathy, or complex regional pain syndrome (CRPS), that messaging system can get stuck in the “on” position. The nerves and pathways that carry pain signals become overactive, amplifying pain even when there’s no new injury driving it. Your nervous system has essentially learned pain, and it keeps replaying that lesson long after it needs to.

This is part of why medications designed to simply mute pain signals often fall short for long-term relief. They quiet the alarm without addressing why it won’t stop ringing.

A Different Approach: Helping the Pathways Reset

Ketamine works differently. Instead of just dulling sensation, it interacts with a receptor in the brain and spinal cord called the NMDA receptor, which plays a central role in how pain signals are processed and amplified. By calming this overactive signaling, ketamine appears to give the nervous system a chance to recalibrate, stepping out of that stuck, high-alert loop and settling into a more normal response to pain.

For many patients, this doesn’t mean pain disappears entirely. It means the volume comes down. Daily tasks that once felt impossible start to feel manageable again. Some patients describe it as the first real break they’ve had from their pain in years, a window where they can finally think clearly and get some real rest.

Pain Rarely Travels Alone

Something we see often in our practice is how deeply chronic pain and emotional wellbeing are intertwined. Living in pain day after day wears on mood, sleep, and mental resilience, and that emotional weight can, in turn, make the pain itself feel more intense. It becomes a loop that’s hard to break from either direction.

This is one of the reasons ketamine infusion therapy can feel different from other treatments patients have tried. Alongside its effects on pain pathways, ketamine has shown promise in lifting mood and easing the anxiety and low points that so often accompany long-term pain. Treating both at once, the physical and the emotional, can make a real difference in how present patients feel in their own lives again.

What Treatment Looks Like Here

We know that trying something new after years of disappointment takes courage. That’s why every patient starts with an unhurried consultation, where we take time to understand your pain history, what you’ve already tried, and what your goals are. From there, we build a treatment plan suited to you, not a one-size-fits-all protocol.

Infusions themselves are calm and low-key. You’ll settle into a private, comfortable room while a member of our medical team monitors you closely throughout the session, which typically runs about 40 to 60 minutes. Many patients describe the experience as deeply relaxing, and most are able to head home shortly afterward.

Relief tends to build gradually across a series of sessions. For many patients, the effects can last for weeks or months, with occasional follow-up infusions helping to maintain that progress over time.

You Deserve Options That Actually Help

If chronic pain has become the background noise of your life, please know that struggling to find relief isn’t a reflection of anything you’ve done wrong. Pain is complicated, and it often takes an approach that looks beyond simply masking symptoms.

We’d love to talk with you about whether ketamine infusion therapy could be part of your path forward. Reach out to Tranquility Ketamine to schedule a consultation and start a conversation about what real relief could look like for you.

Ketamine Infusion Therapy: The Promising Alternative to Opioids for Chronic Pain Relief

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Chronic pain is a widespread problem that affects millions of people worldwide. Various conditions, such as arthritis, fibromyalgia, cancer, and nerve damage, can lead to a chronic pain diagnosis. Unfortunately, the treatment of chronic pain can be a challenging and complex process, and traditional pain management approaches such as opioids have many drawbacks. In recent years, ketamine infusion therapy has emerged as a promising alternative to Opioids for the treatment of chronic pain. This blog post will explore why ketamine infusion therapy is better for chronic pain than opioids.

What are opioids, and how do they work?

Opioids are a class of drugs that are used to treat moderate to severe pain. They work by attaching to specific receptors in the brain and spinal cord, reducing the perception of pain. Opioids are effective painkillers, but they also have significant drawbacks. Opioids can be highly addictive, and prolonged use can lead to tolerance, dependence, and addiction. They can also cause a wide range of side effects, including nausea, constipation, drowsiness, and respiratory depression. In addition, long-term use of opioids can damage the liver, kidneys, and other organs.

What is ketamine infusion therapy?

Ketamine infusion therapy involves the administration of low doses of ketamine, a dissociative anesthetic, into the bloodstream. The therapy has been used for decades as an anesthetic in surgical procedures, but it is only in recent years that its potential as a treatment for chronic pain has been recognized. Ketamine is believed to work by blocking NMDA receptors in the brain, which are involved in the perception of pain.

Advantages of ketamine infusion therapy over opioids for chronic pain

1. Ketamine is not addictive.

One of the most significant advantages of ketamine infusion therapy over opioids is that it is not addictive. While opioids can be highly addictive, ketamine does not produce the same level of dependence. Ketamine does not activate the same reward pathways in the brain as opioids, meaning there is little risk of addiction or abuse.

Ketamine does not cause respiratory depression.

Another significant advantage of ketamine infusion therapy is that it does not cause respiratory depression, a potentially life-threatening side effect of opioids. Respiratory depression occurs when opioids suppress the central nervous system, leading to decreased breathing rate and depth. This can cause oxygen levels in the blood to drop, which can be fatal. Ketamine does not suppress the central nervous system to the same extent as opioids, which means that it does not cause respiratory depression.

2. Ketamine is effective for neuropathic pain.

Neuropathic pain, which is caused by damage to the nerves, is notoriously difficult to treat with opioids. Ketamine, on the other hand, is effective in the treatment of neuropathic pain. Ketamine blocks NMDA receptors in the brain, which are involved in the transmission of pain signals. This means that ketamine can be an effective treatment for chronic neuropathic pain.

3. Ketamine has fewer side effects than opioids.

Opioids can cause a wide range of side effects, including nausea, constipation, drowsiness, and cognitive impairment. Ketamine, on the other hand, has fewer side effects than opioids. The most common side effects of ketamine infusion therapy are mild and include dissociation, dizziness, and changes in perception. These side effects usually resolve quickly after the infusion is stopped.

4. Ketamine has a rapid onset of action.

Another advantage of ketamine infusion therapy over opioids is its rapid onset of action. Ketamine is administered intravenously, which means that it enters the bloodstream quickly and starts to work within minutes. This makes it an effective option for patients who need rapid pain relief.

Conclusion

In summary, ketamine infusion therapy is a promising alternative to opioids for the treatment of chronic pain. Ketamine is not addictive, does not cause respiratory depression, is effective for neuropathic pain, has fewer side effects than opioids, and has a rapid onset of action. While ketamine infusion therapy is not appropriate for all patients, it should be considered a treatment option for those struggling with chronic pain who have not responded to traditional pain management approaches. As always, patients should consult with their healthcare provider to determine if ketamine infusion therapy is right for them.

 

To learn more about this innovative treatment, click here or call 505-639-4973

 

brain chronic pain

Ketamine Infusion Therapy; An Alternative to Opioids for Chronic Pain

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Experiencing daily pain for over 12 weeks is categorized by the medical community as Chronic Pain. Chronic pain affects a staggering 50-100 million adults in the U. S. yearly and over 1.5 billion people worldwide. Another disappointing statistic, chronic pain is the leading cause of long-term disability in the U. S. today. Traditionally, opioid analgesics are the first choice when treating patients with chronic pain.

Opioids and Addiction

Often, in the beginning, opioids provide pain relief for most patients. Unfortunately, these effects don’t last. Over a relatively short period of time, the neurons involved respond to the overexpression of the opiate receptors, leading to decreased effectiveness of these medications. As a result of the reduced efficacy, larger doses administered more frequently are needed. As a result, patients develop medication tolerance, dependence, and addiction.

 

Statistics on opioid abuse show a severe national crisis affecting public health and socio-economic welfare. According to the National Institute on Drug Abuse, approximately 21 to 29 percent of patients prescribed opioids for chronic pain misuse them. In 2019, nearly 50,000 people in the United States died from opioid-involved overdoses. 

Ketamine Infusion Therapy: An Alternative Treatment

Ketamine has been the choice for surgical use for its anesthetic properties for many decades. In recent years, Ketamine Infusions have been used to treat depression, chronic pain, and many other mood disorders. The administration of intravenous low-dose Ketamine is surprisingly effective in rapidly improving the symptoms of depression, posttraumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), and other mental health conditions, as well as chronic pain syndromes. Numerous studies have been conducted at reputable research centers from 2000 to the present, supporting its use for these conditions.

The Science of Ketamine

When Ketamine binds to N-methyl-D-aspartate (NMDA) receptors in your brain, it helps increase the amount of a glutamate neurotransmitter. Glutamate activates connections in another brain receptor, which triggers the release of molecules that allow neurons to find new pathways with which to communicate in your brain. This process is called synaptogenesis, and it’s thought to affect your mood and thought patterns.

Ketamine Infusion Therapy for Chronic Pain

It has been shown that Ketamine infusions rapidly provide up to a 50% decrease in patient-reported pain levels in patients that respond to these treatments. Ketamine is particularly effective for many chronic pain syndromes, particularly neuropathic pain syndromes, such as chronic regional pain syndrome (CRPS). Ketamine is thought to improve chronic pain in a novel way by blocking the N-methyl-D-aspartate (NMDA) receptor. This NMDA blockade is believed to allow the pain pathways in the brain and spine to “reset,” allowing a more normalized response to pain signals from the body’s nerves. This resetting of the pain pathways may last for weeks to months and can be maintained with occasional booster treatments, as needed.

Ketamine allows a decrease in painful symptoms as well as a decrease in the need for opioid medications. In addition, there is an evident overlay of depressive symptoms and chronic anxiety for many patients suffering from chronic pain disorders. Therefore, Ketamine’s ability to decrease the symptoms of depression and anxiety can lessen the compounding effect these conditions have on the patient’s pain level.

To learn more about Ketamine Infusion Therapy, click here or call 505-639-4973 to schedule a private consultation.

Tranquility Ketamine Clinic is a leading provider of Ketamine infusion therapy in Albuquerque, New Mexico. Founded by two experienced emergency room physicians with over 50 years of combined practice administering Ketamine in the emergency department, the clinic provides effective treatments for depression, PTSD (posttraumatic stress disorder), chronic pain, OCD (obsessive-compulsive disorder), anxiety, stress, and burnout in comfortable private rooms at its Northeast Albuquerque location.

Brain image of ketamine infusion

The Ketamine Infusion Experience

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Ketamine is a dissociative anesthetic with various mechanisms of action and binds to multiple receptors in the brain. Consequently, it is difficult to pin down the precise mode of action, and it appears that there are various mechanisms through which Ketamine exerts its action on the brain. Ketamine Infusion Therapy is used to treat depression, PTSD, OCD, chronic anxiety, and chronic pain. One question that gets asked often is what does it feel like during and after the treatment?

 

Just like any drug therapy, ketamine infusion therapy can be different for everyone, and experiences may be different from one infusion to the other  In our clinic, the infusion itself is done intravenously, typically over 45 minutes, followed by a 45-60-minute period of rest while the effect of the medication wears off. The dosage and time vary depending on the individual and the disorder being treated.

 

How Will I feel During treatment?

The initial sensations begin about 5 minutes into the treatment and can last about 90 minutes. These effects wear off quickly after the infusion is stopped. Some describe the sensation of being in a dream or of being deeply relaxed. Others report an altering of perception and feeling a bit “out of their body.”  Avid meditators find their ability to achieve a prolonged sense of stillness and peace is heightened beyond anything they have experienced during a regular mediation session. Overall, patients find the experience to be intense yet pleasurable. Although the benefit from Ketamine does not require dissociation, many providers, including ourselves, believe the dissociative state is an essential and desirable state for profound psychological and spiritual growth and feel it to be a critical factor in our patient’s healing journey.

 

Will I Feel Sleepy or Sedated?

Low-dose Ketamine does not typically cause a sense of sedation, and many patients report they are pretty sharp mentally and can work through their thoughts and feelings clearly and calmly for the first time in their life. While the intensity of the effects wears off quickly, we always caution there may be some feeling of imbalance and delayed reaction time for a few hours, and we advise you not to drive or operate heavy machinery following your treatment. We require that you have someone to drive you home before we begin the infusion and ask that you abstain from alcohol or recreational drugs for at least 24 hours before and after treatment.

 

How Quickly Does It Take Effect?

For some patients, temporary relief of symptoms can occur within hours of the first infusion. However, it is important to note; this relief is typically short-lived. After several infusions over two-to-three weeks, this lifting of the depressive or anxious symptoms can be complete or markedly improved. However, it may last several weeks or months before beginning to fade. In addition, single-dose “booster” treatments at a period of two weeks to a few months after the initial induction infusions have been shown to prolong the antidepressant effect of the medication in many patients.

 

If you or someone you know suffers from Major Depressive Disorder, PTSD, OCD, anxiety, or chronic pain and you would like to learn more, call us at 505-639-4973 or click here to schedule an appointment.

free from chronic pain

Treating Chronic Pain Without Opioids

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Chronic pain is defined as the experience of daily pain for over 12 weeks. What is shocking is that according to the statistics, chronic pain affects between 50-100 million adults in the U. S. yearly and over 1.5 billion people worldwide. In addition, chronic pain is the leading cause of long-term disability in the U. S. today. Traditionally, patients with chronic pain are treated with opioid analgesics.

Opioids Aren’t the Answer

Initially, opioids provide pain relief for most patients. Unfortunately, these effects are short-lived. Over a relatively short period of time, the neurons involved respond by the overexpression of the opiate receptors, leading to decreased responsiveness and effectiveness to these medications. As a result of the reduced efficacy, larger doses administered more frequently are needed. Too often, patients develop medication tolerance, dependence, and addiction.

 

According to the National Institute on Drug Abuse, approximately 21 to 29 percent of patients prescribed opioids for chronic pain misuse them. In 2019, nearly 50,000 people in the United States died from opioid-involved overdoses. Statistics like these are glaring evidence of a severe national crisis affecting public health and socio-economic welfare.

Ketamine Infusion Therapy: An Alternative Treatment

Ketamine has been popular for surgical use for its anesthetic properties since the 1960s. Over the last several years, Ketamine Infusions have been used to treat depression, chronic pain, and a number of other mood disorders. The administration of intravenous low-dose Ketamine is surprisingly effective in rapidly improving the symptoms of depression, posttraumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), and other mental health conditions, as well as chronic pain syndromes. This effect is supported by numerous studies conducted at reputable research centers from 2000 to the present.

How Does Ketamine Work?

When Ketamine binds to N-methyl-D-aspartate (NMDA) receptors in your brain, it helps increase the amount of a neurotransmitter called glutamate. Glutamate activates connections in another brain receptor, which triggers the release of molecules that allow neurons to find new pathways to communicate with each other in your brain. This process is called synaptogenesis, and it’s thought to affect your mood and thought patterns.

Ketamine Infusion Therapy for Chronic Pain

Ketamine infusions have been shown to rapidly provide up to a 50% decrease in patient-reported pain levels in patients that respond to these treatments. Ketamine is particularly effective for many chronic pain syndromes, particularly neuropathic pain syndromes, such as chronic regional pain syndrome (CRPS). Ketamine is thought to improve chronic pain in a novel way by blocking the N-methyl-D-aspartate (NMDA) receptor. This NMDA blockade is believed to allow the pain pathways in the brain and spine to “reset,” allowing a more normalized response to pain signals from the body’s nerves. This resetting of the pain pathways may last for weeks to months and can be maintained with occasional booster treatments, as needed.

Ketamine allows a decrease in painful symptoms as well as a decrease in the need for opioid medications. In addition, there is a clear overlay of depressive symptoms and chronic anxiety for many patients suffering from chronic pain disorders. Therefore, Ketamine’s ability to decrease the symptoms of depression and anxiety can lessen the compounding effect these conditions have on the patient’s pain level.

To learn more about Ketamine Infusion Therapy, click here or call 505-639-4973 to schedule a private consultation.

Tranquility Ketamine Clinic is a leading provider of Ketamine infusion therapy in Albuquerque, New Mexico. Founded by two experienced emergency room physicians with over 50 years combined practice administering Ketamine in the emergency department, the clinic provides effective treatments for depression, PTSD (posttraumatic stress disorder), chronic pain, OCD (obsessive-compulsive disorder), anxiety, stress, and burnout in comfortable private rooms at its Northeast Albuquerque location.